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In a world where plant-based lifestyles are on the rise, the power of foods such as broccoli, celery, and tofu, which are rich in flavonoids, is becoming clearer. Flavonoids are phenolic compounds produced by plants that are essential for plant development and defense and have long been said to have therapeutic and preventive effects against cancer and heart disease. However, the exact process of how our bodies metabolize flavonoids remains unclear.
An international team of researchers led by visiting researcher Tsutomu Shimada and Professor Shigeo Takenaka of the Graduate School of Human Life and Ecology at Osaka Metropolitan University, has shed light on the mechanism of three major flavonoids – naringenin, apigenin and genistein – and the processes by which the body metabolizes them. Molecular docking analyses revealed that human enzymes modify flavonoids in a similar way to how plants modify flavonoids.
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“The results of this research are fundamental in elucidating the correlation between the metabolism of flavonoids in the body and their potential health benefits,” explained Professor Takenaka.
Reference: Nagayoshi H, Murayama N, Kim V, et al. Oxidation of naringenin, apigenin, and genistein by human family 1 cytochrome P450 enzymes and comparison of interaction of apigenin with human P450 1B1.1 and Scutellaria P450 82D.1. Chem Res Toxicol. 2023;36(11):1778-1788. doi: 10.1021/acs.chemrestox.3c00229
This article has been republished from the following materials. Note: material may have been edited for length and content. For further information, please contact the cited source.
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Reliver Pro is a dietary supplement formulated with a blend of natural ingredients aimed at supporting liver health
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I strongly recommend stay away from this site. My own encounter with it was nothing but dismay along with suspicion of deceptive behavior. Proceed with extreme caution, or even better, look for a trustworthy service to fulfill your requirements.
I highly advise stay away from this platform. My personal experience with it was purely frustration as well as suspicion of fraudulent activities. Exercise extreme caution, or alternatively, look for a trustworthy site to fulfill your requirements.
Bravo for such an insightful post on this beautiful Monday! It sets a positive tone for the week ahead. Adding more visuals could make your future posts even more engaging and visually appealing.
Your post is a beacon of positivity this beautiful Monday. The insights provided are invaluable and uplifting. Adding more visuals might just be the cherry on top for future posts.
This post is the highlight of my Monday! It’s wonderfully written and full of insights. Incorporating more visuals could make your future posts even more engaging and enjoyable.
I highly advise stay away from this platform. My own encounter with it was only dismay as well as suspicion of scamming practices. Be extremely cautious, or alternatively, find a trustworthy service to fulfill your requirements.
I highly advise steer clear of this site. My personal experience with it has been only dismay as well as suspicion of fraudulent activities. Exercise extreme caution, or better yet, seek out a trustworthy platform to meet your needs.
I urge you to avoid this site. My own encounter with it was purely dismay as well as concerns regarding fraudulent activities. Exercise extreme caution, or alternatively, find an honest site to meet your needs.
I strongly recommend steer clear of this site. My personal experience with it was purely frustration as well as suspicion of fraudulent activities. Be extremely cautious, or alternatively, seek out a more reputable platform to fulfill your requirements.
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